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Role of TGF-β1 and C-Kit Mutations in the Development of Hepatocellular Carcinoma in Hepatitis C Virus-Infected Patients: in vitro Study

Transforming growth factor beta (TGF-β) acts as a tumor-suppressing cytokine in healthy tissues and non-malignant tumors. Yet, in malignancy, TGF-β can exert the opposite effects that can promote proliferation of cancer cells. C-Kit plays a prominent role in stem cell activation and liver regeneration after injury. However, little is known about the cross-talk between TGF-β and C-Kit and its role

Artificial Intelligence

MetaFlow: An interactive user-friendly workflow for automated analysis of whole genome shotgun sequencing metagenomic data

Metagenomics is a rapidly emerging field that is concerned with the study of microbial communities 'microbiomes' on both levels of taxonomic classification and functional annotation. Targeted amplicon (16S rRNA) and whole genome shotgun (WGS) sequencing are the two main sequencing strategies in metagenomics. As amplicon sequencing provides a cheap way to classify the composition of a microbial

Artificial Intelligence

AmpliconNet: Sequence Based Multi-layer Perceptron for Amplicon Read Classification Using Real-time Data Augmentation

Taxonomic assignment is the core of targeted metagenomics approaches that aims to assign sequencing reads to their corresponding taxonomy. Sequence similarity searching and machine learning (ML) are two commonly used approaches for taxonomic assignment based on the 16S rRNA. Similarity based approaches require high computation resources, while ML approaches dont need these resources in prediction

Artificial Intelligence
Healthcare

The H3ABioNet helpdesk: An online bioinformatics resource, enhancing Africa's capacity for genomics research

Background: Currently, formal mechanisms for bioinformatics support are limited. The H3Africa Bioinformatics Network has implemented a public and freely available Helpdesk (HD), which provides generic bioinformatics support to researchers through an online ticketing platform. The following article reports on the H3ABioNet HD (H3A-HD)'s development, outlining its design, management, usage and

Artificial Intelligence

An encryption protocol for NEQR images based on one-particle quantum walks on a circle

Quantum walks are generalizations of random walks that have extensive applications in various fields including cryptography, quantum algorithms, and quantum networking. Discrete quantum walks can be seen as nonlinear mappings between quantum states and position probability distributions, and this mathematical property may be thought of as an imprint of chaotic behavior and consequently used to

Artificial Intelligence

Design and implementation of robust firefighting/intruder detection system using fuzzy logic decision control (FIDFUZ)

This research focuses on using quantifiable methods for using the IoT as a main support to firefighting/intruder detection. From our research, we have found numerous researches associated to supplying remote services by means of portable sensors and communication technologies. We represent in our research a unique Smart Firefighting/lntruder Detection System with the support of Fuzzy Logic

Artificial Intelligence

First Observation of the Directed Flow of D0 and D0 ̄ in Au+Au Collisions at sNN =200 GeV

We report the first measurement of rapidity-odd directed flow (v1) for D0 and D0̄ mesons at midrapidity (|y|

Artificial Intelligence

A Real-Time Social Network- Based Traffic Monitoring Vehicle Tracking System

Social networking has become an essential part of our daily lives. tTe integration of social networking communication model and Internet of Things (IoT) provides the users with a greater advantage than the benefit of using each one alone. This paper presents a real-time traffic monitoring and vehicle tracking for the public or private transportation sectors. The proposed system uses a social

Artificial Intelligence

Logistics 4.0: Definition and Historical Background

Logistics 4.0 is very important to the current business world. It is expected to revolutionize a lot of business aspects. However, there is no clear definition for Logistics 4.0 till now. Due to its important impact on businesses nowadays, this work aims at reaching a definition for Logistics 4.0. The process of defining Logistics 4.0 is performed through reviewing the historical background

Merging supply chain and blockchain technologies

Technology is a significant component in our everyday life. Many definitions exist for technology, one of which is “all the knowledge, products, processes, tools, methods and systems employed in the creation of goods or in providing services”. Due to the impact of technological innovations on organizations, competitiveness levels are raised noticeably. Hence, reliable means of information exchange